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Medications & Supplements

  • Selamectin (brand names: Revolution®, Paradyne®, Stronghold®, Chanhold®) is an avermectin antiparasitic used topically to treat parasites in dogs and cats, both on and off label. Use with caution in sick or underweight pets, or dogs with the MDR1 mutation.

  • Selamectin + sarolaner is used topically on the skin to treat various parasites, both on and off-label, and prevent heartworm in cats. Side effects are rare but may include hair loss at the application site, gastrointestinal upset, skin reactions, or neurologic signs. It should be used with caution in sick or underweight cats. If a negative reaction occurs, please call your veterinary office.

  • Selegiline is typically given by mouth and is used off and on label in dogs and cats to treat signs due to cognitive dysfunction syndrome, pituitary-dependent Cushing’s disease, anxiety, and certain phobias.

  • Sertraline is given by mouth and is an antidepressant used off label in dogs and cats to treat a variety of behavior disorders, including anxiety, obsessive compulsive disorder, and aggression.

  • Ophthalmic autologous serum is a blood-derived product used to treat corneal ulcers in animals. Ophthalmic autologous serum is part of the blood and is collected directly from the patient. It is in liquid form.

  • Sildenafil (brand name: Viagra®) is a vasodilator used off label to treat high blood pressure in the blood vessels of the lungs (pulmonary hypertension) in dogs and sometimes cats. It is also used to treat megaesophagus. In cattle, it may be useful in treating uterine conditions such as endometritis.

  • Silver sulfadiazine topical is an antimicrobial used to treat skin infections and burns in cats, dogs, and exotic pets. It is used off label in veterinary medicine. Silver sulfadiazine topical comes in a topical cream.

  • Simethicone is an anti-gas agent used to help treat pain, bloating, and flatulence caused by excessive gas in the gastrointestinal tract of cats, dogs, and other animals. It works as an anti-foaming agent by reducing surface tension on gas bubbles.

  • Sirolimus delayed-release tablets (Felycin®-CA1) are conditionally approved by the Food and Drug Administration (FDA) in the United States for the management of ventricular hypertrophy in cats with hypertrophic cardiomyopathy (HCM) that is subclinical (not yet showing symptoms. Sirolimus is a hazardous drug.

  • Slippery elm is given by mouth and is used over the counter to treat cough and stomach upset in dogs and cats. Give as directed by your veterinarian.